Membranes & Molecules Seminars

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Copper homeostasis in a host restricted pathogen,Bordetella pertussis

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Dr. Françoise JACOB-DUBUISSON Center for Infection and Immunity, Pasteur Institute of Lille, LILLE, France Copper is an essential transition metal whose redox properties are used for various enzymatic oxido-reductions and in electron transfer chains. It is also toxic to living beings, and therefore its cellular concentration must be strictly controlled. Copper is part of the […]

Le mécénat scientifique de la famille Rothschild

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Pauline Prevost Marcilhacy Maître de conférences en histoire del’art à l’université de Lille Membre de l’Institut de recherches historiques du Septentrion (IRHiS, UMR 8529) https://pro.univ-lille.fr/pauline-prevost-marcilhacy/ Les Rothschild sont reconnus comme étant les plus importants collectionneurs et mécènes des XIXè et XXè siècles. Ce sont en effet plus de 130 000 œuvres d'art qui ont enrichi […]

Sexe, genre et stéréotypes: L’égalité femme/homme au CNRS

ZOOM meeting

Dr Jean-Louis VERCHER Institut des Sciences du Mouvement, UMR 7287, Université Aix-Marseille Chargé de mission à l'INSB section 26 "Cognition" Représentant de l'INSB au comité "égalité-parité" du CNRS

Optoproteomics elucidates the interactome of L-type amino acid transporter 3 (LAT3) using non-natural aminoacids

Shixin Ye-Lehmann, Ph.DINSERM tenured researcher (CR) INSERM research unit U1195 Diseases and Hormones of the Nervous System Cross-linking mass-spectroscopy requires small crosslinkers to identify interactome. We report the application of genetic code expansion in combination with photo-crosslinking chemistry, as we termed “optoproteomics”, to identify proteins interaction with the human L-type membrane amino acid transporter 3 […]

Sterol transport through niemann-pick type c proteins from the rnd superfamily

Bjørn Panyella Pedersen, Associate Prof. Department of Molecular Biology and Genetics, Aarhus University, Denmark Niemann-Pick type C (NPC) proteins are essential for sterol homeostasis in all eukaryotes. They drive sterol integration into the vacuolar/lysosomal membrane before redistribution to other cellular membranes. My group uses a combination of crystallography, cryo-electronmicroscopy, biochemical and in vivo studies on […]

Organelles communicate thanks to flexible and polyspecific proteins

Daniel Lévy Institut Curie, UMR168 CNRS, Paris In eukaryotes, endoplasmic reticulum (ER) establishes direct contact with all other organelles. Within these contact zones, called membrane contact sites (MCS), protein complexes bridge membranes and ensure a specific function. There is not yet structure of protein complexes involved in MCS. The ER protein VAP-A (VAMP-associated protein A), […]

February 6 2024. Dr. Sophie Combet

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Dr. Sophie Combet Tracking the solution structures of membrane proteins by scattering and modeling LLB, Paris-Saclay