Our laboratory gathers biologists, physicists and chemists who are interested in the structure, structural dynamics and physical chemistry of membrane proteins, either in vivo within a lipid bilayer, or in vitro after solubilization and stabilization by classical or alternative surfactants such as amphipols.

Our proteins of interest cover various domains of fundamental and medical biology:

Energy coupling & supramolecular organization of respiratory chain complexes

Respiratory chain complexes

Uncoupling protein biochemistry

Molecular Signalisation Pathway of GPGRs

HEDGEHOG Pathway

GPCR

Study of Signal Transduction by GPCRs

GPCR

GPCR crystallisation

Transport & Membrane Dynamics in Bacteria

Biochemistry of Iron Transport in Haemophilus

Membrane systems
dynamics

efflux pumps

Efflux pumps in bacteria

Molecular synthesis of Amphipols and ligands &
Biophysical Approaches

Amphipols

Chemistry of ligands

CRyo EM structure

Electron Microscopy

SEC MALlS

SEC MALLS