Our laboratory gathers biologists, physicists and chemists who are interested in the structure, structural dynamics and physical chemistry of membrane proteins, either in vivo within a lipid bilayer, or in vitro after solubilization and stabilization by classical or alternative surfactants such as amphipols.
Our proteins of interest cover various domains of fundamental and medical biology:
Energy coupling & supramolecular organization of respiratory chain complexes
Respiratory chain complexes
Uncoupling protein biochemistry
Molecular Signalisation Pathway of GPGRs
HEDGEHOG Pathway
Study of Signal Transduction by GPCRs
GPCR crystallisation
Transport & Membrane Dynamics in Bacteria
Biochemistry of Iron Transport in Haemophilus
Membrane systems
dynamics
Efflux pumps in bacteria
Molecular synthesis of Amphipols and ligands &
Biophysical Approaches
Amphipols
Chemistry of ligands
Electron Microscopy
