Laboratory of Physical and Chemical Biology of Membrane Proteins
Our laboratory gathers biologists, physicists and chemists who are interested in the structure, structural dynamics and physical chemistry of membrane proteins, either in membrane mimetic systems (liposomes or nanodiscs), or in classical detergent solutions or alternative surfactants such as amphipols.
Following the footsteps of Jean Perrin who created the institute together with Baron Edmond de Rothschild, we develop fundamental, interdisciplinary research for health and environment.
This team is Amazing
Our research themes
Research within the laboratory is organized in four main themes.
& supramolecular organization of respiratory chain complexes
& membrane dynamics
Molecular synthesis of Amphipols and ligands
& biophysical approaches
Apply for fellowship “Structure function study of a tripartite efflux pump from the ABC superfamily, in its lipid environment” CALL2
PI: Martin Picard, Manuela Zoonens Our laboratory has acknowledged experience in
FP-DYNAMO-PARIS fellowship programme is proposing 21 fellowships for the most
Tool Box Development
In addition, all members of the unit contribute to the development of our tool box for membrane proteins studies, which includes: NMR, mass spectrometry, crystallography, physical-chemistry of surfactants, membrane protein production and synthetic biology.
to membrane protein production within the T7 expression system.
More recently we engineered new bacterial hosts with modified
membrane lipid composition.
All bacterial hosts are available upon request.
FP-DYNAMO-PARIS FELLOWSHIP PROGRAMME
The programme is proposing 21 fellowships for the most brilliant students from all over the world.
This project is funded by the European Union’s Horizon 2020 Research and Innovation Programme under the Marie Skłodowska-Curie actions (grant agreement No 101034407).
In our laboratory, there will be 4 fellowship topics.
SyBOrg, creating a synthetic membrane organelle in E. Coli and C. reinhardtii
structural studies of
Membrane & Molecules Seminars
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Facts and Figures
Research is a collective adventure where cohesion of the team is essential. We foster social activities to stimulate exchange of expertise, mentoring and synergies between research topics. Social life around the Institute is highly attractive for students and early researchers.
in the lab