CryoEM structure solution at the IBPC

Single particle cryo-electron microscopy is an invaluable tool for 3D structure solution of macromolecular complexes such as those studied at the IBPC. It is complementary to X-ray crystallography and we can now reach atomic resolution details.
We collect our cryo-EM data at large facilites such as the ESRF Titan Krios microscope
And we process the images locally with the computing power provided by the bioinformatics core facility and the Laboratoire de Biochimie théorique GPU cluster